• BCL6
  • B cell lymphoma 6


Technical InfoEdit

Staining PatternEdit

  • Nuclear

Expression in Normal TissuesEdit

  • Germinal center B-cells

Expression in Neoplastic EntitiesEdit

Tumor name % Positive Staining Number of Cases

Intermediate/Uncertain Malignant PotentialEdit
Tumor name % Positive Staining Number of Cases

Tumor name % Positive Staining Number of Cases
*Germinal center type of diffuse large B-cell lymphoma (DLBCL)[1]
  • NOTE: DLBCL that is BCL-6+ can only be considered germinal center type in the context of NEGATIVE MUM1 (IRF4) staining. In other words, BCL-6+/MUM1+ DLBCL is considered to be "activated (non-germinal center) type". [1]

Expression in Non-Neoplastic EntitiesEdit

Pertinent NegativesEdit

This antigen is typically NOT expressed by the following entities:

Practical Uses / PanelsEdit

Common PitfallsEdit

Related Links/Other ResourcesEdit


  1. 1.0 1.1 Mod Pathol. 2004 Jul;17(7):847-56.

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