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CD21 (also known as complement receptor 2)[1] is an antigen that is expressed on the surface of B lymphocytes[2] and follicular dendritic cells.[3]

SynonymsEdit

AntibodiesEdit

Technical InfoEdit

Staining PatternEdit

Expression in Normal TissuesEdit

  • B lymphocytes[2]
  • Follicular dendritic cells [3]

Expression in Neoplastic EntitiesEdit

BenignEdit
Tumor name % Positive Staining Number of Cases


Intermediate/Uncertain Malignant PotentialEdit
Tumor name % Positive Staining Number of Cases


MalignantEdit
Tumor name % Positive Staining Number of Cases
Follicular dendritic cell tumors

Expression in Non-Neoplastic EntitiesEdit

Practical Uses / PanelsEdit

Common PitfallsEdit

ReferencesEdit

  1. Frank K, Atkinson JP (2001). "Complement system." In Austen KF, Frank K, Atkinson JP, Cantor H. eds. Samter's Immunologic Diseases, 6th ed. Vol. 1, p. 281-298, Philadelphia: Lippincott Williams & Wilkins, ISBN 0781721202.
  2. 2.0 2.1 Entrez Gene: CR2 complement component (3d/Epstein Barr virus) receptor 2
  3. 3.0 3.1 J Exp Med. 1997 Jan 6;185(1):165-70.

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