• Cyclin D1
  • bcl-1


Technical InfoEdit

Staining PatternEdit

Expression in Normal TissuesEdit

Expression in Neoplastic EntitiesEdit

Tumor name % Positive Staining Number of Cases

Intermediate/Uncertain Malignant PotentialEdit
Tumor name % Positive Staining Number of Cases

Tumor name % Positive Staining Number of Cases
Mantle cell lymphoma 72%[1]-100%[2] 23/32[1], 10/10[2]

Expression in Non-Neoplastic EntitiesEdit

Pertinent NegativesEdit

This antigen is typically NOT expressed by the following entities:

  • Small Lymphocytic Lymphoma/Chronic Lymphocytic Leukemia [1]
  • Follicular Lymphoma[3]

Practical Uses / PanelsEdit

Common PitfallsEdit

Related Links/Other ResourcesEdit


  1. 1.0 1.1 1.2 Am J Clin Pathol. 1997 Sep;108(3):302-7.
  2. 2.0 2.1 Mod Pathol. 1998 Nov;11(11):1046-51.
  3. Am J Pathol. 1994 Jul;145(1):86-96.

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