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Cytokeratin 903 (34βE12)

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  • Cytokeratin 903 expression in sarcomatoid carcinoma.

SynonymsEdit

  • Cytokeratin 903
  • Keratin 903
  • K903
  • 34βE12
  • 34betaE12
  • High Molecular Weight Cytokeratin (K903 is one example of an HMWCK)

AntibodiesEdit

  • 34βE12

Technical InfoEdit

Staining PatternEdit

  • Cytoplasmic

Expression in Normal TissuesEdit

  • Basal cells (prostate, etc)
  • Myoepithelial cells (breast)

Expression in Neoplastic EntitiesEdit

BenignEdit
Tumor name % Positive Staining (Sensitivity) Number of Cases Specificity Comments


Intermediate/Uncertain Malignant PotentialEdit
Tumor name % Positive Staining (Sensitivity) Number of Cases Specificity Comments


MalignantEdit
Tumor name % Positive Staining (Sensitivity) Number of Cases Specificity Comments
  • Carcinomas (some, particularly squamous cell carcinoma and some examples of sarcomatoid carcinoma)

Expression in Non-Neoplastic EntitiesEdit

Pertinent NegativesEdit

This antigen is typically NOT expressed by the following entities:

Practical Uses / PanelsEdit

Common PitfallsEdit

Related Links/Other ResourcesEdit

ReferencesEdit

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