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SynonymsEdit

  • HER1
  • c-erb-B1

AntibodiesEdit

Technical InfoEdit

Staining PatternEdit

  • Membranous and cytoplasmic

Expression in Normal TissuesEdit

Expression in Neoplastic EntitiesEdit

BenignEdit
Tumor name % Positive Staining (Sensitivity) Number of Cases Specificity Comments


Intermediate/Uncertain Malignant PotentialEdit
Tumor name % Positive Staining (Sensitivity) Number of Cases Specificity Comments


MalignantEdit
Tumor name % Positive Staining (Sensitivity) Number of Cases Specificity Comments
Additional Comments:Edit

Expression in Non-Neoplastic EntitiesEdit

Pertinent NegativesEdit

This antigen is typically NOT expressed by the following entities:

Practical Uses / PanelsEdit

  • Membranous staining predicts response to epidermal growth factor receptor inhibitors in metastatic colon adenocarcinoma and head/neck squamous cell carcinoma.

Common PitfallsEdit

Related Links/Other ResourcesEdit

ReferencesEdit

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