Synonyms[]
CTNNB1
Antibodies[]
Technical Info[]
Staining Pattern[]
- Nuclear or nuclear and cytoplasmic
Expression in Normal Tissues[]
Expression in Neoplastic Entities[]
Benign[]
| Tumor name | % Positive Staining | Number of Cases | ||
| Pilomatrixoma | 100%[1] | 21/21 [1] | ||
| Superficial (palmar and plantar) fibromatosis | ||||
Intermediate/Uncertain Malignant Potential[]
| Tumor name | % Positive Staining | Number of Cases |
| Desmoid-type fibromatosis | ||
| Solid pseudopapillary tumor (pancreas) | ||
Malignant[]
| Tumor name | % Positive Staining | Number of Cases |
| Colorectal Adenocarcinoma (nuclear)[2] | ||
| Pilomatrix carcinoma | 100%[1] | 5/5[1] |
Expression in Non-Neoplastic Entities[]
Practical Uses / Panels[]
Common Pitfalls[]
References[]
- ↑ 1.0 1.1 1.2 1.3 Hassanein AM, Glanz SM. Beta-catenin expression in benign and malignant pilomatrix neoplasms. Br J Dermatol. 2004 Mar;150(3):511-6.
- ↑ Wong SC, Lo ES, Lee KC, Chan JK, HSiao WL. Prognostic and Diagnostic Significance of Beta-catenin Nuclear Immunostaining in Colorectal Cancer. Clinical Cancer Research 2004; 10(4): 1401-8.