Synonyms[]
Antibodies[]
Technical Info[]
Staining Pattern[]
- Nuclear[1]
Expression in Normal Tissues[]
- Embryonal notochord [1]
- Spermatogonia
Expression in Neoplastic Entities[]
Benign[]
| Tumor name | % Positive Staining | Number of Cases |
Intermediate/Uncertain Malignant Potential[]
| Tumor name | % Positive Staining | Number of Cases |
Malignant[]
| Tumor name | % Positive Staining | Number of Cases |
| Chordoma (including extra-axial type) | 98%[1] | 53/54[1] |
Expression in Non-Neoplastic Entities[]
Practical Uses / Panels[]
- Brachyury can be used to differentiate chordomas(brachyury+) from chondroid tumors (brachyury-) when cytokeratin expresssion in chordomas is weak or patchy (a potential problem in needle biopsy).[1]