Synonyms[]
Antibodies[]
Technical Info[]
Staining Pattern[]
- Nuclear and cytoplasmic staining
Expression in Normal Tissues[]
Expression in Neoplastic Entities[]
Expression in Neoplastic Entities[]
Benign[]
| Tumor name | % Positive Staining (Sensitivity) | Number of Cases | Specificity | Comments |
| Adrenal cortical adenoma: | 100%[1] | 16/16[1] | ||
Intermediate/Uncertain Malignant Potential[]
| Tumor name | % Positive Staining (Sensitivity) | Number of Cases | Specificity | Comments |
| Paraganglioma | 25%[1] | 5/20[1] | ||
Malignant[]
| Tumor name | % Positive Staining (Sensitivity) | Number of Cases | Specificity | Comments |
| Mesothelioma | 100%[2] | 60/60[2] | ||
| Adrenal cortical carcinoma | 92%[1] | 11/12[1] | ||
Expression in Non-Neoplastic Entities[]
Pertinent Negatives[]
Practical Uses / Panels[]
- Can be used with WT-1 and cytokeratin 5/6 to differentiate epithelioid mesothelioma (positive for all 3 markers) from pulmonary adenocarcinoma (negative for all 3 markers)[2]
- Can be used in differentiating tumors of adrenocortical origin (calretinin positive) from those of adrenal medullary origin (calretinin negative)[1]