Synonyms[]
Antibodies[]
Technical Info[]
Staining Pattern[]
Expression in Normal Tissues[]
- nearly all apical surfaces of ductular and glandular epithelium
- normal plasma cells are often EMA positive
- renal distal convoluted tubules[1]
- renal collecting ducts[1]
- perineural cells
Expression in Neoplastic Entities[]
Benign[]
Tumor name | % Positive Staining (Sensitivity) | Number of Cases | Specificity | Comments |
Meningioma | 100%[2] | 22[2] | ||
Perineurioma | ||||
Intermediate/Uncertain Malignant Potential[]
Tumor name | % Positive Staining (Sensitivity) | Number of Cases | Specificity | Comments |
Malignant[]
Tumor name | % Positive Staining (Sensitivity) | Number of Cases | Specificity | Comments | |
Epithelioid sarcoma | 85%[3] | 20[3] | |||
Synovial Sarcoma | 91%[4] | 23[4] | |||
Low Grade Fibromyxoid Sarcoma | |||||
Expression in Non-Neoplastic Entities[]
Pertinent Negatives[]
The antigen is typically NOT expressed in the following:
- Schwannoma[2]
Practical Uses / Panels[]
- EMA may be useful if pancytokeratin is negative in a suspected synovial sarcoma, as it is more sensitive than cytokeratin in this setting.[5]