HMB-45

• HMB-45 expression in a rare example of angiomyolipoma with epithelial cyst. Ovarian-like stroma cells also stain in this case.
• HMB-45 expression in a rare example of angiomyolipoma with epithelial cyst. Ovarian-like stroma cells also stain in this case.
• Granular expression of HMB-45 in an angiomyolipoma (PEComa).
• HMB-45 expression in primary cutaneous PEComa.
• HMB-45 expression in primary cutaneous PEComa.
• HMB-45 expression in primary cutaneous PEComa.
• HMB-45 expression in primary cutaneous PEComa.
• HMB-45 expression in a malignant melanoma.
• HMB-45 expression in a malignant melanoma.
• HMB-45 expression in a malignant melanoma.

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Synonyms

• HMB = Human Melanoma Black
• gp100
• Pmel 17

Staining Pattern

• Cytoplasmic

Expression in Neoplastic Entities

Benign

Tumor name	% Positive Staining (Sensitivity)	Number of Cases	Specificity	Comments
Blue nevus				(diffuse)

Intermediate/Uncertain Malignant Potential

Tumor name	% Positive Staining (Sensitivity)	Number of Cases	Specificity	Comments
PEComa

Malignant

Tumor name	% Positive Staining (Sensitivity)	Number of Cases	Specificity	Comments
Melanoma
Clear cell sarcoma