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Tryptase is a serine protease enzyme found in mast cell granules. Immunostaining for tryptase can be useful in identification of mast cells and mast cell disease.

Synonyms[]

  • Mast cell tryptase

Antibodies[]

Technical Info[]

Staining Pattern[]

  • Cytoplasmic

Expression in Normal Tissues[]

  • Mast Cells

Expression in Neoplastic Entities[]

Benign[]


Intermediate[]
  • Mast Cell Disease / Mastocytosis
Malignant[]

Expression in Non-Neoplastic Entities[]

Pertinent Negatives[]

This antigen is typically NOT expressed by the following entities:

Practical Uses / Panels[]

Common Pitfalls[]

Related Links/Other Resources[]

References[]

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