Tyrosinase (monophenol monooxygenase)is an enzyme that is responsible for converting tyrosine into melanin in human melanocytes. The tyrosinase gene is regulated by the Microphthalmia-associated transcription factor (MiTF) gene product.[1]
Synonyms[]
Antibodies[]
Technical Info[]
Staining Pattern[]
Expression in Normal Tissues[]
- Melanocytes
Expression in Neoplastic Entities[]
Benign[]
- Melanocytic Nevi
Intermediate[]
Malignant[]
- Melanoma
Expression in Non-Neoplastic Entities[]
Pertinent Negatives[]
This antigen is typically NOT expressed by the following entities: