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GATA3

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SynonymsEdit

AntibodiesEdit

Technical InfoEdit

Staining PatternEdit

Expression in Normal TissuesEdit

Expression in Neoplastic EntitiesEdit

BenignEdit
Tumor name % Positive Staining (Sensitivity) Number of Cases Specificity Comments


Intermediate/Uncertain Malignant PotentialEdit
Tumor name % Positive Staining (Sensitivity) Number of Cases Specificity Comments


MalignantEdit
Tumor name % Positive Staining (Sensitivity) Number of Cases Specificity Comments
Urothelial carcinoma 67%
Additional Comments:Edit

Expression in Non-Neoplastic EntitiesEdit

Pertinent NegativesEdit

This antigen is typically NOT expressed by the following entities:

Practical Uses / PanelsEdit

  • GATA3 is very specific for urothelial carcinoma when the differential diagnosis includes prostate and renal carcinomas.  GATA3 sensitivity for urothelial carcinoma is somewhat poor (67%). 

Common PitfallsEdit

Related Links/Other ResourcesEdit

ReferencesEdit

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