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Human Herpesvirus 8 (HHV-8)

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  • HHV-8 expression in Kaposi sarcoma.
  • HHV-8 expression in Kaposi sarcoma.
  • HHV-8 expression in Kaposi sarcoma.
  • HHV-8 expression in Kaposi sarcoma.
  • HHV-8 expression in Kaposi sarcoma.

SynonymsEdit

  • Human herpesvirus 8
  • HHV-8
  • Kaposi sarcoma-associated herpesvirus
  • LANA-1

AntibodiesEdit

Technical InfoEdit

Staining PatternEdit

  • Nuclear

Expression in Normal TissuesEdit

Expression in Neoplastic EntitiesEdit

BenignEdit


Intermediate/Uncertain Malignant PotentialEdit
  • Multicentric Castleman's disease[1]


MalignantEdit
  • Kaposi sarcoma[1]
  • Primary effusion lymphoma[1]

Expression in Non-Neoplastic EntitiesEdit

Pertinent NegativesEdit

This antigen is typically NOT expressed by the following entities:

Practical Uses / PanelsEdit

  • Kaposi sarcoma versus other vascular mimics

Common PitfallsEdit

Related Links/Other ResourcesEdit

ReferencesEdit

  1. 1.0 1.1 1.2 Proc Natl Acad Sci U S A. 1999 April 13; 96(8): 4546–4551.

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