Pathology Resident Wiki
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MOC-31 is an antibody that reacts with an epithelial surface glycoprotein.

Synonyms[]

Antibodies[]

Technical Info[]

Staining Pattern[]

  • Membranous

Expression in Normal Tissues[]

  • Epithelium

Expression in Neoplastic Entities[]

Benign[]
Tumor name % Positive Staining (Sensitivity) Number of Cases Specificity Comments


Intermediate/Uncertain Malignant Potential[]
Tumor name % Positive Staining (Sensitivity) Number of Cases Specificity Comments


Malignant[]
Tumor name % Positive Staining (Sensitivity) Number of Cases Specificity Comments
Many carcinomas
Additional Comments:[]

Expression in Non-Neoplastic Entities[]

Pertinent Negatives[]

This antigen is typically NOT expressed by the following entities:

  • Mesothelioma

Practical Uses / Panels[]

  • Adenocarcinoma (positive) versus mesothelioma (negative)

Common Pitfalls[]

Related Links/Other Resources[]

References[]

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