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MPM2

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SynonymsEdit

AntibodiesEdit

Technical InfoEdit

Staining PatternEdit

  • Cytoplasmic (but only considered as a mitosis if cytoplasmic staining is accompanied by chromosomal condensation)[1]

Expression in Normal TissuesEdit

Expression in Neoplastic EntitiesEdit

BenignEdit
IntermediateEdit
MalignantEdit

Expression in Non-Neoplastic EntitiesEdit

Practical Uses / PanelsEdit

  • MPM2 immunostain has been used to highlight the presence of mitoses in benign nevi[1]

Common PitfallsEdit

ReferencesEdit

  1. 1.0 1.1 K Glatz, C Hartmann, M Antic, H Kutzner. Frequent Mitotic Activity in Banal Melanocytic Nevi Uncovered by Immunohistochemical Analysis. Am J Dermatopathol. Oct 2010. 32(7):643-649.

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