• MCPyV


  • CM2B4

Technical InfoEdit

Staining PatternEdit

  • Nuclear

Expression in Normal TissuesEdit

Expression in Neoplastic EntitiesEdit


Intermediate/Uncertain Malignant PotentialEdit

  • Merkel cell carcinoma (+ in 67%)[1]

Expression in Non-Neoplastic EntitiesEdit

Pertinent NegativesEdit

This antigen is typically NOT expressed by the following entities:

  • Pulmonary neuroendocrine tumors[1]
  • Combined neuroendocrine and squamous carcinomas of the skin[1]

Practical Uses / PanelsEdit

  • May be used to differentiate Merkel cell carcinoma from metastatic neuroendocrine tumor from the lung.

Common PitfallsEdit

Related Links/Other ResourcesEdit


  1. 1.0 1.1 1.2 Am J Surg Pathol. 2009 September ; 33(9): 1378–1385

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