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SynonymsEdit

AntibodiesEdit

  • PE-10

Technical InfoEdit

Staining PatternEdit

Expression in Normal TissuesEdit

Expression in Neoplastic EntitiesEdit

BenignEdit
Tumor name % Positive Staining (Sensitivity) Number of Cases Specificity Comments


Intermediate/Uncertain Malignant PotentialEdit
Tumor name % Positive Staining (Sensitivity) Number of Cases Specificity Comments


MalignantEdit
Tumor name % Positive Staining (Sensitivity) Number of Cases Specificity Comments
Bronchioloalveolar Carcinoma (non-mucinous type) 100%[1]
Pulmonary Adenocarcinoma 60%[1]
Small cell carcinoma of lung 20%[1]
Atypical carcinoid of lung 40%[1]
Additional Comments:Edit

Expression in Non-Neoplastic EntitiesEdit

Pertinent NegativesEdit

This antigen is typically NOT expressed by the following entities:

  • Adenocarcinomas of the breast, kidney, large bowel and ovaries were all negative[1]
  • Metastatic adenocarcinoma to lung and pleura (n=26) were all negative[1]
  • Pulmonary squamous cell carcinoma[1]

Practical Uses / PanelsEdit

Common PitfallsEdit

Related Links/Other ResourcesEdit

ReferencesEdit

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Histopathology. 1995 Jul;27(1):57-60.

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