• transducin-like enhancer of split


Technical InfoEdit

Staining PatternEdit

  • Nuclear

Expression in Normal TissuesEdit

Expression in Neoplastic EntitiesEdit

  • Moderate staining is occasionally seen in schwannoma and solitary fibrous tumor/hemangiopericytoma.[1]

Intermediate/Uncertain Malignant PotentialEdit

  • Synovial sarcoma (strong, diffuse staining in 91/94 molecularly confirmed synovial sarcomas)[1]

Expression in Non-Neoplastic EntitiesEdit

Pertinent NegativesEdit

This antigen is typically NOT expressed by the following entities:

Practical Uses / PanelsEdit

Common PitfallsEdit

  • Weak staining may be seen in many types of soft tissue tumors.[1]

Related Links/Other ResourcesEdit


  1. 1.0 1.1 1.2 Am J Surg Pathol. 2007 Feb;31(2):240-6.

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