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  • Villin expression in brush border of colonic adenocarcinoma.
  • Villin expression in brush border of colonic adenocarcinoma.
  • Villin expression in brush border of colonic adenocarcinoma.

SynonymsEdit

AntibodiesEdit

Technical InfoEdit

Staining PatternEdit

  • Apical membranous (brush border) staining

Expression in Normal TissuesEdit

  • Brush border of GI tract and renal tubules

Expression in Neoplastic EntitiesEdit

BenignEdit


Intermediate/Uncertain Malignant PotentialEdit


MalignantEdit
  • Colonic adenocarcinoma[1]
  • Clear cell renal cell carcinoma (RCC)[1]
  • Pancreatic adenocarcinoma (some)[1]
  • Endometrial adenocarcinoma (some)[1]

Expression in Non-Neoplastic EntitiesEdit

Pertinent NegativesEdit

This antigen is typically NOT expressed by the following entities:

  • Ovarian carcinoma[1]
  • Breast adenocarcinoma[1]
  • Mesothelioma[1]

Practical Uses / PanelsEdit

Common PitfallsEdit

Related Links/Other ResourcesEdit

ReferencesEdit

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Roland Moll, Sylvie Robine, Brigitte Dudouet and Daniel Louvard. Villin: a cytoskeletal protein and a differentiation marker expressed in some human adenocarcinomas. VIRCHOWS ARCHIV B. Volume 54, Number 1, 155-169.

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